PeptideDB

H-His-Ser-OH

CAS No.: 21438-60-8

The 1:1 complex of H-His-Ser-OH with Co(II)(Cys-Gly) was shown to cleave DNA by hydrolysis at physiological pH. Cleavage
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CAS 21438-60-8
Sequence H-His-Ser-OH
Sequence Single HS
Molecular Formula C9H14N4O4
Molecular Weight 242.24
Technology Synthetic
Storage -20°C, avoid light, cool and dry place
Application Di- and Tripeptides
Description The 1:1 complex of H-His-Ser-OH with Co(II)(Cys-Gly) was shown to cleave DNA by hydrolysis at physiological pH. Cleavage has also been observed employing the analogous Co complex with His-Phe.
References 1.  Tissue specific increase of the catalytic subunits of the 26S proteasome by indirect antioxidant dithiolethione in mice: enhanced activity for degradation of abnormal protein. M.-K.Kwak et al., Life Sci., 80, 2411 (2007)