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H-D-Pro-Pro-Glu-NH2

CAS No.: 1021646-82-1

In the presence of as little as 1 mol% H-D-Pro-Pro-Glu-NH2, a broad range of aldehydes and nitroolefins react readily wi
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CAS 1021646-82-1
Sequence H-D-Pro-Pro-Glu-NH2
Sequence Single pPE-NH2
Molecular Formula C15H24N4O5
Molecular Weight 340.38
Technology Synthetic
Storage -20°C, avoid light, cool and dry place
Application Di- and Tripeptides
Description In the presence of as little as 1 mol% H-D-Pro-Pro-Glu-NH2, a broad range of aldehydes and nitroolefins react readily with each other. The resulting γ-nitroaldehydes were obtained in excellent yields and stereoselectivities at room temperature.
References 1.  Maxadilan, a PAC1 receptor agonist from sand flies. E.A.Lerner et al., Peptides, 28, 1651 (2007) 2.  Tripeptides of the type H-D-Pro-Pro-Xaa-NH2 as catalysts for asymmetric 1,4-addition reactions: structural requirements for high catalytic efficiency. M.Wiesner et al., Chem. Eur. J., 15, 10103 (2009)