H-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu-Leu-Val-Tyr-Ser-OH Renin Inhibitors and Substrates Catalog

CAS	20845-02-7
Sequence	H-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu-Leu-Val-Tyr-Ser-OH
Sequence Single	DRVYIHPFHLLVYS
Molecular Formula	C85H123N21O20
Molecular Weight	1759.04
Synonyms	Tetradecapeptide Renin Substrate (horse), Angiotensinogen (1-14) (horse), Preangiotensinogen (1-14) (horse), Angiotensinogen (1-14), porcine
Technology	Synthetic
Storage	-20°C, avoid light, cool and dry place
Application	Cardiovascular System & Diseases
Description	H-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu-Leu-Val-Tyr-Ser-OH also called Tetradecapeptide Renin Substrate (horse), Angiotensinogen (1-14) (horse), Preangiotensinogen (1-14) (horse), Angiotensinogen (1-14), porcine, is a renin substrate. H-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu-Leu-Val-Tyr-Ser-OH is readily cleaved by human kidney renin and human cathepsin D.
References	1. Purification and characterization of an N-terminal acidic amino acid-specific aminopeptidase from soybean cotyledons (Glycine max). M.Asano et al., Biosci. Biotechnol. Biochem., 74, 113 (2010) 2. Comparison of angiotensinogen and tetradecapeptide as substrates for human renin. Substrate dependence of the mode of inhibition of renin by a statine-containing hexapeptide. D.K.Stammers et al., Arch. Biochem. Biophys., 258, 413 (1987)

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