| CAS | 167875-35-6 |
| Sequence | H-Arg-Val-Leu-psi(CH2NH)Phe-Glu-Ala-Nle-NH2 |
| Sequence Single | RVL-psi(CH2NH)FEA-Nle-NH2 |
| Molecular Formula | C40H69N11O8 |
| Molecular Weight | 832.06 |
| Technology | Synthetic |
| Storage | -20°C, avoid light, cool and dry place |
| Application | Infectious Disease |
| Description | The peptide H-Arg-Val-Leu-psi(CH2NH)Phe-Glu-Ala-Nle-NH2 containing a reduced peptide bond was found to be a competitive inhibitor of the HIV-1 protease (Ki = 50 nM). |
| References | 1. Structure of complex of synthetic HIV-1 protease with a substrate-based inhibitor at 2.3 A resolution. M.Miller et al., Science, 246, 1149 (1989) |