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H-Arg-Val-Leu-psi(CH2NH)Phe-Glu-Ala-Nle-NH2

CAS No.: 167875-35-6

The peptide H-Arg-Val-Leu-psi(CH2NH)Phe-Glu-Ala-Nle-NH2 containing a reduced peptide bond was found to be a competitive
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CAS 167875-35-6
Sequence H-Arg-Val-Leu-psi(CH2NH)Phe-Glu-Ala-Nle-NH2
Sequence Single RVL-psi(CH2NH)FEA-Nle-NH2
Molecular Formula C40H69N11O8
Molecular Weight 832.06
Technology Synthetic
Storage -20°C, avoid light, cool and dry place
Application Infectious Disease
Description The peptide H-Arg-Val-Leu-psi(CH2NH)Phe-Glu-Ala-Nle-NH2 containing a reduced peptide bond was found to be a competitive inhibitor of the HIV-1 protease (Ki = 50 nM).
References 1.  Structure of complex of synthetic HIV-1 protease with a substrate-based inhibitor at 2.3 A resolution. M.Miller et al., Science, 246, 1149 (1989)