| CAS | 39537-23-0 |
| Sequence | H-Ala-Gln-OH |
| Sequence Single | AQ |
| Molecular Formula | C8H15N3O4 |
| Molecular Weight | 217.23 |
| Technology | Synthetic |
| Storage | -20°C, avoid light, cool and dry place |
| Application | Cell Culture|Di- and Tripeptides|Food Research & Nutrition |
| Description | H-Ala-Gln-OH, a glutamine dipeptide, is benefit for the antioxidant system, attenuating inflammation, and may modulate the heat shock protein (HSP) response in catabolic situations. |
| References | 1. Purification and characterization of dipeptidyl peptidase I from human spleen. M.J.McGuire et al., Arch. Biochem. Biophys., 295, 280 (1992) 2. The adaptation of BHK cells to a non-ammoniagenic glutamate-based culture medium. A.Christie and M.Butler, Biotechnol. Bioeng., 64, 298 (1999) 3. Influence of two glutamine-containing dipeptides on growth of mammalian cells. E.Roth et al., In Vitro Cell Dev. Biol., 24, 696 (1988) 4. Glutamine-containing dipeptides in parenteral nutrition. P.Fürst et al., JPEN J. Parenter. Enteral Nutr., 14, 118S (1990) 5. Efficacy of parenteral nutrition supplemented with glutamine dipeptide to decrease hospital infections in critically ill surgical patients. C.F.Estivariz et al., JPEN J. Parenter. Enteral Nutr., 32, 389 (2008) 6. Degradation kinetics of L-alanyl-L-glutamine and its derivatives in aqueous solution. K.Arii et al., Eur. J. Pharm. Sci., 7, 107 (1999) 7. Alanyl-glutamine improves pancreatic β-cell function following ex vivo inflammatory challenge. Cruzat VF,et al. J Endocrinol. 2015 Mar;224(3):261-71. |