| CAS | 73168-24-8 |
| Sequence | β-Mercapto-β,β-cyclopentamethylene-propionyl-Tyr(Me)-Phe-Gln-Asn-Cys-Pro-Arg-Gly-NH2 (Disulfide bond) |
| Sequence Single | β-Mercapto-β,β-cyclopentamethylene-propionyl-Y(Me)FQNCPRG-NH2 |
| Molecular Formula | C52H74N14O12S2 |
| Molecular Weight | 1151.38 |
| Synonyms | Manning Compound, [Pmp1, Tyr(OMe)2, Arg8] Vasopressin |
| Technology | Synthetic |
| Storage | -20°C, avoid light, cool and dry place |
| Application | Cardiovascular System & Diseases |
| Description | (d(CH2)5¹,Tyr(Me)2,Arg8)-Vasopressin also called Manning Compound, [Pmp1, Tyr(OMe)2, Arg8] Vasopressin, is a very potent V1 receptor antagonist (antivasopressor) with almost no antidiuretic activity. |
| References | 1. Vasopressin antagonists allow demonstration of a novel type of vasopressin receptor in the rat adenohypophysis. S.Jard et al., Mol. Pharmacol., 30, 171 (1986) 2. The block of central vasopressin V1 but not V2 receptors suppresses grooming behavior and hypothermia induced by intracerebroventricular vasopressin in male rats. S.Caltabiano et al., Drugs Future, 13, 25 (1988) |
(d(CH2)5¹,Tyr(Me)2,Arg8)-Vasopressin
CAS No.: 73168-24-8
(d(CH2)5¹,Tyr(Me)2,Arg8)-Vasopressin also called Manning Compound, [Pmp1, Tyr(OMe)2, Arg8] Vasopressin, is a very poten
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