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(d(CH2)5¹,D-Tyr(Et)2,Val4,Arg8,des-Gly9)-Vasopressin

CAS No.: 90332-82-4

(d(CH2)5¹,D-Tyr(Et)2,Val4,Arg8,des-Gly9)-Vasopressin also called LS-186846, SK&F 101926, is an antagonist of both the a
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CAS 90332-82-4
Sequence β-Mercapto-β,β-cyclopentamethylene-propionyl-D-Tyr(Et)-Phe-Val-Asn-Cys-Pro-Arg-NH2 (Disulfide bond)
Sequence Single β-Mercapto-β,β-cyclopentamethylene-propionyl-y(Et)FVNCPR-NH2
Molecular Formula C51H74N12O10S2
Molecular Weight 1079.36
Synonyms LS-186846, SK&F 101926
Technology Synthetic
Storage -20°C, avoid light, cool and dry place
Application Cardiovascular System & Diseases
Description (d(CH2)5¹,D-Tyr(Et)2,Val4,Arg8,des-Gly9)-Vasopressin also called LS-186846, SK&F 101926, is an antagonist of both the antidiuretic and vasopressor responses of vasopressin.
References 1.  Potent V2 vasopressin antagonists with structural changes at their C-terminals. W.H.Sawyer, Peptides, 9, 157 (1988)