PeptideDB

((Cys31,Nva34)-Neuropeptide Y (27-36))2

CAS No.: 172997-92-1

((Cys31,Nva34)-Neuropeptide Y (27-36))2 is the first peptide-based specific Y1 receptor antagonist (Ki = 36 ± 8 nM). Th
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CAS 172997-92-1
Sequence (H-Tyr-Ile-Asn-Leu-Cys-Thr-Arg-Nva-Arg-Tyr-NH2)2 (Disulfide bond)
Sequence Single (YINLCTR-Nva-RY-NH2)2 (Disulfide bond)
Molecular Formula C116H186N36O28S2
Molecular Weight 2597.11
Technology Synthetic
Storage -20°C, avoid light, cool and dry place
Application Obesity Research
Description ((Cys31,Nva34)-Neuropeptide Y (27-36))2 is the first peptide-based specific Y1 receptor antagonist (Ki = 36 ± 8 nM). This dimerization had enhanced both the selectivity and affinity to Y1 receptors. This antagonist has properties similar to non-peptide antagonists.