(Cys18)-Atrial Natriuretic Factor (4-18) amide (mouse, rabbit, rat) Natriuretic Peptides Catalog

CAS	111863-73-1
Sequence	H-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Ile-Asp-Arg-Ile-Gly-Ala-Cys-NH2 (Disulfide bond)
Sequence Single	RSSCFGGRIDRIGAC-NH2
Molecular Formula	C64H107N25O19S2
Molecular Weight	1594.84
Synonyms	C-ANF (4-23), (Des-Gln18,des-Ser19,des-Gly20.22,des-Leu21)-Atrial Natriuretic Peptide (4-23) amide (mouse, rabbit, rat), Des[Gln18, Ser19, Gly20,22, Leu21] ANP (4-23), amide, rat
Technology	Synthetic
Storage	-20°C, avoid light, cool and dry place
Application	Cardiovascular System & Diseases
Description	(Cys18)-Atrial Natriuretic Factor (4-18) amide (mouse, rabbit, rat) also called C-ANF (4-23), (Des-Gln18,des-Ser19,des-Gly20.22,des-Leu21)-Atrial Natriuretic Peptide (4-23) amide (mouse, rabbit, rat), Des[Gln18, Ser19, Gly20,22, Leu21] ANP (4-23), amide, rat, binds with high affinity to approximately 99% of ANF receptors in the isolated perfused rat kidney. It competes effectively with biologically active atrial peptides for binding sites but is devoid of agonist or antagonist action on the generation of cGMP in vascular smooth muscle and endothelial cells in culture.
References	1. Four-hour infusions of synthetic atrial natriuretic peptide in normal volunteers. J.Biollaz et al., Hypertension, 8, II96 (1986)

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