| CAS | 107090-96-0 |
| Sequence | H-Pro-Phe-Cys-Asn-Ala-Phe-Thr-Gly-Cys-NH2 (Disulfide bond) |
| Sequence Single | PFCNAFTGC-NH2 |
| Molecular Formula | C42H57N11O11S2 |
| Molecular Weight | 956.11 |
| Synonyms | CCAP, Crustacean Cardioactive Peptide (CCAP), amide |
| Technology | Synthetic |
| Storage | -20°C, avoid light, cool and dry place |
| Application | Cardiovascular System & Diseases |
| Description | Crustacean Cardioactive Peptide also called CCAP, Crustacean Cardioactive Peptide (CCAP), amide, is a peptide with the sequence of PFCNAFTGC-NH2. Native and synthetic Crustacean Cardioactive Peptide displayed high ino- and chronotropic effects on a semi-isolated crab heart preparation. |
| References | 1. Pancreatic polypeptide reduces appetite and food intake in humans. R.L.Batterham et al., J. Clin. Endocrinol. Metab., 88, 3989 (2003) 2. Unusual cardioactive peptide (CCAP) from pericardial organs of the shore crab Carcinus maenas. J.Stangier et al., Proc. Natl. Acad. Sci. USA, 84, 575 (1987) 3. Crustacean cardioactive peptide in the sphinx moth, Manduca sexta. H.K.Lehman et al., Peptides, 14, 735 (1993) 4. Regulation of the crab heartbeat by crustacean cardioactive peptide (CCAP): central and peripheral actions. T.J.Fort et al., J. Neurophysiol., 97, 3407 (2007) |