PeptideDB

Cortistatin-29 (human)

CAS No.: 1815618-16-6

Cortistatin-29 (human) (CST (human)) represents an antiinflammatory, immunomodulatory factor with a potential multistep
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CAS 1815618-16-6
Sequence Pyr-Glu-Gly-Ala-Pro-Pro-Gln-Gln-Ser-Ala-Arg-Arg-Asp-Arg-Met-Pro-Cys-Arg-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Ser-Ser-Cys-Lys-OH (Disulfide bond)
Sequence Single pEEGAPPQQSARRDRMPCRNFFWKTFSSCK
Molecular Formula C149H223N47O42S3
Molecular Weight 3440.9
Technology Synthetic
Storage -20°C, avoid light, cool and dry place
Application Immunomodulating Agents|Inflammation Research
Description Cortistatin-29 (human) (CST (human)) represents an antiinflammatory, immunomodulatory factor with a potential multistep therapeutic use in the treatment of septic shock and Crohn’s disease.
References 1.  Development of selective inhibitors and substrate of matrix metalloproteinase-12. L.Devel et al., J. Biol. Chem., 281, 11152 (2006) 2.  Cortistatin, an antiinflammatory peptide with therapeutic action in inflammatory bowel disease. E.Gonzalez-Rey et al., Proc. Natl. Acad. Sci. USA, 103, 4228 (2006)