| CAS | 301544-78-5 |
| Sequence | H-Ile-Ala-Val-Val-Gln-Asp-Trp-Gly-His-His-Arg-Ala-Thr-NH2 |
| Sequence Single | IAVVQDWGHHRAT-NH2 |
| Molecular Formula | C66H101N23O17 |
| Molecular Weight | 1488.67 |
| Technology | Synthetic |
| Storage | -20°C, avoid light, cool and dry place |
| Description | Compstatin control peptide is a negative control of Compstatin. Compstatin is a potent complement system C3 inhibitor. |
| References | 1. Inhibition of human complement by a C3-binding peptide isolated from a phage-displayed random peptide library. Sahu et al (1996). J.Immunol. 157 884 PMID: 8752942 2. Compstatin, a peptide inhibitor of C3, prolongs survival of ex vivo perfused pig xenografts. Fiane et al (1999). Xenotransplantation 6 52 PMID: 10355733 3. Essential role of the C5a receptor in E coli-induced oxidative burst and phagocytosis revealed by a novel lepirudin-based human whole blood model of inflammation. Mollnes et al (2002). Blood 100 1869 PMID: 12176911 2. Binding kinetics, structure-activity relationship, and biotransformation of the complement inhibitor compstatin. Sahu A, et al. J Immunol. 2000 Sep 1;165(5):2491-9. |