| CAS | 683750-83-6 |
| Sequence | H-Glu-Pro-Leu-Gln-Leu-Lys-Met-OH |
| Sequence Single | EPLQLKM |
| Molecular Formula | C38H67N9O11S |
| Molecular Weight | 858.06 |
| Technology | Synthetic |
| Storage | -20°C, avoid light, cool and dry place |
| Application | Cell Culture|Regenerative Medicine |
| Description | Bonemarrow-Derived Mesenchymal Stem Cells Affinity Peptide is a heptapeptide with the sequence of EPLQLKM, it binds to graphene with high specificity. Additionally, the peptide shows a high affinity for bone marrow stromal cells. |
| References | 1. Activation of demineralized bone matrix by genetically engineered human bone morphogenetic protein-2 with a collagen binding domain derived from von Willebrand factor propolypeptide. B.Chen et al., J. Biomed. Mater. Res. A, 80, 428 (2007) 2. Peptides binding to the hunger hormone ghrelin. M.Vodnik et al., Horm. Metab. Res. , 45, 372 (2013) 3. Binding of solvated peptide (EPLQLKM) with a graphene sheet via simulated coarse-grained approach. S.Sheikholeslami et al., J. Chem. Phys., 140, 204901 (2014) 4. Covalent immobilization of MSC-affinity peptide on poly(L-lactide-co-ε-caprolactone) copolymer to enhance stem cell adhesion and retention for tissue engineering applications. M.Shafiq et al., Macromol. Res., 24, 986 (2016) 5. Polycaprolactone electrospun mesh conjugated with an MSC affinity peptide for MSC homing in vivo. Z.Shao et al., Biomaterials, 33, 3375 (2012) 6. The interplay of T1- and T2-relaxation on T1-weighted MRI of hMSCs induced by Gd-DOTA-peptides. Limin Cao, et al. Biomaterials. 2014 Apr;35(13):4168-74. |