CAS | 412961-36-5 |
Sequence | H-Val-Gly-Arg-Pro-Glu-Trp-Trp-Met-Asp-Tyr-Gln-Lys-Arg-Tyr-Gly-OH |
Sequence Single | RPEWWMDYQKRYG |
Molecular Formula | C91H127N25O23S |
Molecular Weight | 1971.23 |
Synonyms | Bovine Adrenal Medulla Peptide (8-22), BAM-15, BAM (8-22) |
Technology | Synthetic |
Storage | -20°C, avoid light, cool and dry place |
Application | Opioid Research |
Description | BAM-22P (8-22) also called Bovine Adrenal Medulla Peptide (8-22), BAM-15, BAM (8-22), is a endogenous peptide fragment first isolated from bovine adrenal medulla. BAM-22P (8-22) is a selective agonist for the sensory neuron specific receptor (EC50 values are 28 and 14 nM for SNSR3 and SNSR4, respectively). |
References | 1. Galanin-like peptide stimulates food intake in the rat. Y.Matsumoto et al., Neurosci. Lett., 322, 67 (2002) 2. BAM8-22 peptide produces itch and nociceptive sensations in humans independent of histamine release. P.Sikand et al., J. Neurosci., 31, 7563 (2011) 3. Proenkephalin A gene products activate a new family of sensory neuron--specific GPCRs. P.M.C.Lembo et al., Nat. Neurosci., 5, 201 (2002) |