PeptideDB

BAM-22P (8-22)

CAS No.: 412961-36-5

BAM-22P (8-22)also called Bovine Adrenal Medulla Peptide (8-22), BAM-15, BAM (8-22), is a endogenous peptide fragment fi
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CAS 412961-36-5
Sequence H-Val-Gly-Arg-Pro-Glu-Trp-Trp-Met-Asp-Tyr-Gln-Lys-Arg-Tyr-Gly-OH
Sequence Single RPEWWMDYQKRYG
Molecular Formula C91H127N25O23S
Molecular Weight 1971.23
Synonyms Bovine Adrenal Medulla Peptide (8-22), BAM-15, BAM (8-22)
Technology Synthetic
Storage -20°C, avoid light, cool and dry place
Application Opioid Research
Description BAM-22P (8-22) also called Bovine Adrenal Medulla Peptide (8-22), BAM-15, BAM (8-22), is a endogenous peptide fragment first isolated from bovine adrenal medulla. BAM-22P (8-22) is a selective agonist for the sensory neuron specific receptor (EC50 values are 28 and 14 nM for SNSR3 and SNSR4, respectively).
References 1.  Galanin-like peptide stimulates food intake in the rat. Y.Matsumoto et al., Neurosci. Lett., 322, 67 (2002) 2.  BAM8-22 peptide produces itch and nociceptive sensations in humans independent of histamine release. P.Sikand et al., J. Neurosci., 31, 7563 (2011) 3.  Proenkephalin A gene products activate a new family of sensory neuron--specific GPCRs. P.M.C.Lembo et al., Nat. Neurosci., 5, 201 (2002)