Autocamtide-2-Related Inhibitory Peptide Protein Kinase Related Peptides Catalog

CAS	167114-91-2
Sequence	H-Lys-Lys-Ala-Leu-Arg-Arg-Gln-Glu-Ala-Val-Asp-Ala-Leu-OH
Sequence Single	KKALRRQEAVDAL
Molecular Formula	C64H116N22O19
Molecular Weight	1497.76
Synonyms	AIP, (Ala9)-Autocamtide-2
Technology	Synthetic
Storage	-20°C, avoid light, cool and dry place
Description	Autocamtide-2-Related Inhibitory Peptide also called AIP, (Ala9)-Autocamtide-2, is a non-phosphorylatable analog of autocamtide-2, it was found to be a highly specific and potent inhibitor of calmodulin-dependent protein Kinase II (IC50= 40 nM) without affecting cyclic AMP-dependent protein kinase, protein kinase C and calmodulin-dependent protein kinase IV.
References	1. Protein-tyrosine phosphatase inhibition by a peptide containing the phosphotyrosyl mimetic, L-O-malonyltyrosine. H.K.Kole et al., Biochem. Biophys. Res. Commun., 209, 817 (1995) 2. A novel highly specific and potent inhibitor of calmodulin-dependent protein kinase II. A.Ishida et al., Biochem. Biophys. Res. Commun., 212, 806 (1995)

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