| CAS | 113-79-1 |
| Sequence | H-Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Arg-Gly-NH2 (Disulfide bond) |
| Sequence Single | CYFQNCPRG-NH2 |
| Molecular Formula | C46H65N15O12S2 |
| Molecular Weight | 1084.25 |
| Synonyms | AVP, Argipressin, (Phe3,Arg8)-Oxytocin, Leiormone, Arginine Antidiuretic Hormone |
| Technology | Synthetic |
| Storage | -20°C, avoid light, cool and dry place |
| Application | Cardiovascular System & Diseases|Pituitary & Hypothalamic Hormones|Veterinary Medicine |
| Description | (Arg8)-Vasopressin also called AVP, Argipressin, (Phe3,Arg8)-Oxytocin, Leiormone, Arginine Antidiuretic Hormone, binds to the V1, V2, V3-vascular arginine vasopressin receptor, with a Kd value of 1.31 nM in A7r5 rat aortic smooth muscle cells for V1. |
| References | 1. PTH(1-34) suppresses appositional bone formation by cultured rat cranial osteoblasts. C.Gray and S.J.Jones, Bone, 23, 453 (1998) 2. Arg-vasopressin increases proliferation of human osteoblast-like cells and decreases production of interleukin-6 and macrophage colony-stimulating factor. A.Lagumdzija et al., Regul. Pept., 121, 41 (2004) 3. Circadian rhythm of melatonin release in pineal gland culture: arg-vasopressin inhibits melatonin release. Y.Isobe et al., Brain Res., 918, 67 (2001) 4. Multiple signaling pathways of V1-vascular vasopressin receptors of A7r5 cells. Thibonnier M, et al. Endocrinology. 1991 Dec;129(6):2845-56. 5. Vasopressin-induced intracellular Ca²⁺ concentration responses in non-neuronal cells of the rat dorsal root ganglion. Moriya T, et al. Brain Res. 2012 Nov 5;1483:1-12. 6. Role of vasopressin in current anesthetic practice. Keun Suk Park, et al. Korean J Anesthesiol. 2017 Jun; 70(3): 245–257. |