| CAS | 197230-90-3 |
| Sequence | Ac-Ala-Thr-Leu-Asp-Ala-Leu-Leu-Ala-Ala-Leu-Arg-Arg-Ile-Gln-NH2 |
| Sequence Single | Ac-ATLDALLAALRRIQ-NH2 |
| Molecular Formula | C69H124N22O19 |
| Molecular Weight | 1565.88 |
| Synonyms | NTR 368, Acetyl-Neurotrophin Receptor (365-378) amide (rat) |
| Technology | Synthetic |
| Storage | -20°C, avoid light, cool and dry place |
| Application | Apoptosis & Necrosis |
| Description | Acetyl-Neurotrophin Receptor (368-381) amide (human) also called NTR 368, Acetyl-Neurotrophin Receptor (365-378) amide (rat), is a peptide derived from p75 neurotrophin receptor (p75NTR) corresponding to residues 368-381 of the human receptor. Acetyl-Neurotrophin Receptor (368-381) amide (human) has helix forming propensity in the presence of micellar lipid. Acetyl-Neurotrophin Receptor (368-381) amide (human) is a potent inducer of neural Apoptosis. |
| References | 1. A cytoplasmic peptide of the neurotrophin receptor p75NTR: induction of apoptosis and NMR determined helical conformation. M R Hileman, et al. FEBS Lett. 1997 Sep 29;415(2):145-54. |