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Acetyl-α-MSH (11-13)

CAS No.: 57899-96-4

Acetyl-α-MSH (11-13) is the acetylated C-terminal tripeptide of α-MSH, it shows both antipyretic and anti-inflammatory
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CAS 57899-96-4
Sequence Ac-Lys-Pro-Val-NH2
Sequence Single Ac-KPV-NH2
Molecular Formula C18H33N5O4
Molecular Weight 383.49
Technology Synthetic
Storage -20°C, avoid light, cool and dry place
Application Di- and Tripeptides|Inflammation Research|Pituitary & Hypothalamic Hormones
Description Acetyl-α-MSH (11-13) is the acetylated C-terminal tripeptide of α-MSH, it shows both antipyretic and anti-inflammatory effects, although to a lesser degree than α-MSH itself.
References 1.  Protease-activated receptor 1 is the primary mediator of thrombin-stimulated platelet procoagulant activity. H.Andersen et al., Proc. Natl. Acad. Sci. USA, 96, 11189 (1999) 2.  Anti-inflammatory activity of alpha-MSH(11-13) analogs: influences of alteration in stereochemistry. M.E.Hiltz et al., Peptides, 12, 767 (1991) 3.  Alpha-MSH peptides inhibit acute inflammation and contact sensitivity. M.E.Hiltz and J.M.Lipton, Peptides, 11, 979 (1990)