| CAS | 128657-47-6 |
| Sequence | Ac-Thr-Ile-Nle-psi(CH2NH)Nle-Gln-Arg-NH2 |
| Sequence Single | Ac-TI-Nle-psi(CH2NH)Nle-QR-NH2 |
| Molecular Formula | C35H67N11O8 |
| Molecular Weight | 769.99 |
| Technology | Synthetic |
| Storage | -20°C, avoid light, cool and dry place |
| Application | Infectious Disease |
| Description | Ac-Thr-Ile-Nle-psi(CH2NH)Nle-Gln-Arg-NH2 is the sequence of the HIV-1 protease inhibitor, it is derived from a known cleavage site of the viral gag-pol poly-protein. Electron density studies showed that this inhibitor binds to the active site of the HIV-1 protease. |
| References | 1. Inhibition of the aspartic proteinase from HIV-2. A.D.Richards et al., FEBS Lett., 253, 214 (1989) |