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Ac-Thr-Ile-Nle-psi(CH2NH)Nle-Gln-Arg-NH2

CAS No.: 128657-47-6

Ac-Thr-Ile-Nle-psi(CH2NH)Nle-Gln-Arg-NH2 is the sequence of the HIV-1 protease inhibitor, it is derived from a known cle
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CAS 128657-47-6
Sequence Ac-Thr-Ile-Nle-psi(CH2NH)Nle-Gln-Arg-NH2
Sequence Single Ac-TI-Nle-psi(CH2NH)Nle-QR-NH2
Molecular Formula C35H67N11O8
Molecular Weight 769.99
Technology Synthetic
Storage -20°C, avoid light, cool and dry place
Application Infectious Disease
Description Ac-Thr-Ile-Nle-psi(CH2NH)Nle-Gln-Arg-NH2 is the sequence of the HIV-1 protease inhibitor, it is derived from a known cleavage site of the viral gag-pol poly-protein. Electron density studies showed that this inhibitor binds to the active site of the HIV-1 protease.
References 1.  Inhibition of the aspartic proteinase from HIV-2. A.D.Richards et al., FEBS Lett., 253, 214 (1989)