| Description | 1. Vitexin has antinociceptive and antispasmodic activities. 2. Vitexin exhibits a prominent first-pass effect. 3. Vitexin has antioxidant, antimyeloperoxidase, and α-glucosidase inhibitory activities. 4. Vitexin can either inhibit or induce activities of CYP2C11 and CYP3A1. 5. Vitexin induces the novel p53-dependent metastatic and apoptotic pathway. 6. Vitexin protects brain against cerebral I/R injury, and this effect may be regulated by mitogen-activated protein kinase (MAPK) and apoptosis signaling pathways. |
| Synonyms | 牡荆素, Apigenin-8-C-glucoside |
| molecular weight | 432.38 |
| Molecular formula | C21H20O10 |
| CAS | 3681-93-4 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 43 mg/mL(99.4 mM) Ethanol: Soluble |
| References | 1. Can ÖD1, Demir Özkay Ü, Üçel Uİ.. Anti-depressant-like effect of vitexin in BALB/c mice and evidence for the involvement of monoaminergic mechanisms[J]. European Journal of Pharmacology, 2013, 699(1-3):250-257. |