| Description | Avicularin (Fenicularin) has anti-allergic, anti-inflammatory, hepatoprotective, antioxidant, anti-tumor and other activities. It ameliorates human hepatocellular carcinoma by modulating the activities of NF-κB(p65), COX-2, and PPAR-γ. In LPS-stimulated RAW 264.7 macrophages, it exerts anti-inflammatory activity by inhibiting the ERK signaling pathway. |
| Synonyms | Fenicularin, 扁蓄苷 |
| molecular weight | 434.35 |
| Molecular formula | C20H18O11 |
| CAS | 572-30-5 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | H2O: 1.15 mg/mL DMSO: Soluble |
| References | 1. Vo V A , Lee J W , Chang J E , et al. Avicularin Inhibits Lipopolysaccharide-Induced Inflammatory Response by Suppressing ERK Phosphorylation in RAW 264.7 Macrophages[J]. Biomolecules and Therapeutics, 2012, 20(6):532-537. |