| Description | 1. alpha-Cyperone (α-Cyperone) is a promising inhibitor of Hla production by S. aureus and protects lung cells from this bacterium. 2. alpha-Cyperone significantly inhibited PGE2 production by suppressing the LPS-induced expression of inducible COX-2 at both the mRNA and the protein levels , downregulated the production and mRNA expression of the inflammatory cytokine IL-6. 3. alpha-Cyperone inhibited actin cytoskeleton polymerization induced by APEC-O78 through down regulating the expression of Nck-2, Cdc42 and Rac1. |
| Synonyms | (+)-α-Cyperone, α-香附酮, α-Cyperone |
| molecular weight | 218.33 |
| Molecular formula | C15H22O |
| CAS | 473-08-5 |
| Storage | store at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 9 mg/mL (41.22 mM) |
| References | 1. Zhang L Y , Lv S , Wu S C , et al. Inhibitory effects of α-cyperone on adherence and invasion of avian pathogenic Escherichia coli O78 to chicken type II pneumocytes[J]. Veterinary Immunology and Immunopathology, 2014, 159(1-2):50-57. |